August 17, 2011New England Journal of Medicine574 citationsOpen Access
View Full PaperPrevention of Intraoperative Awareness in a High-Risk Surgical Population
Structured PICO
Does the BIS protocol prevent intraoperative awareness compared to ETAC in a high-risk surgical population?
P
Population
High-risk surgical population
I
Intervention
BIS protocol
C
Comparator
ETAC group
O
Outcome
Intraoperative awarenesssafety
The BIS protocol was not superior to the ETAC protocol for the prevention of intraoperative awareness in high-risk surgical patients.
Abstract
The superiority of the BIS protocol was not established; contrary to expectations, fewer patients in the ETAC group than in the BIS group experienced awareness. (Funded by the Foundation for Anesthesia Education and Research and others; BAG-RECALL ClinicalTrials.gov number, NCT00682825.).