Why the study?
Does valve design and orientation affect vortex formation and diastolic hydrodynamic efficiency in the left ventricle?
Population
In vitro model evaluating porcine, anti-anatomical, and anatomical valve configurations
Comparison
Valve design and orientation vs Comparison among the different valve…
Design
Preclinical
Authors
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Valve configuration affects LV filling efficiency in porcine models; hypothesis-generating for human prosthetic orientation.
Does valve design and orientation affect vortex formation and diastolic hydrodynamic efficiency in the left ventricle?
Vortex formation dynamics and critical formation number provide quantitative measures of left ventricular filling efficiency, which varies significantly by valve design and orientation.
Pierrakos et al. (2006) studied this question.
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