Why the study?
Do the concentrations of Ca(2+) and K(+) in the dialysis bath affect QT interval prolongation in uraemic patients undergoing haemodialysis?
Do the concentrations of Ca(2+) and K(+) in the dialysis bath affect QT interval prolongation in uraemic patients undergoing haemodialysis?
The concentrations of calcium and potassium in the dialysis bath significantly influence ventricular repolarization duration in uremic patients, which may guide electrolyte choice during hemodialysis to prevent arrhythmias.
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May warrant bath electrolyte adjustments to limit repolarization shifts; hypothesis-generating for arrhythmia outcome trials.
Changes in ventricular repolarization duration associated with HD largely depend on the concentrations of Ca(2+) and K(+) in the dialysis bath. These findings may have important implications for the choice of the electrolytes concentration of the dialysis bath during the HD session.
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Genovesi et al. (2008) studied this question.
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