Why the study?
Does haemodialysis with low calcium and potassium concentrations prolong ventricular repolarization in haemodialysis patients?
Population
Haemodialysis (HD) patients and an in silico model of human cardiomyocyte action potential
Comparison
Haemodialysis with low dialysate calcium or low… vs Haemodialysis with high dialysate calcium or…
Design
Other
Authors
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Alerts to possible QTc effects of low-Ca/K dialysate in HD; leaves open arrhythmia risk for prospective trials.
Does haemodialysis with low calcium and potassium concentrations prolong ventricular repolarization in haemodialysis patients?
Low dialysate calcium and potassium concentrations during haemodialysis significantly prolong the QTc interval, suggesting a potential arrhythmogenic risk that can be predicted by computational modeling.
Severi et al. (2007) studied this question.
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