What does this research mean for the field?

During hemodialysis, acute increases in serum calcium cause a proportional shortening of the Q-oTc interval, while decreases in serum potassium are associated with a prolongation of the Q-eTc interval. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1987Japanese Heart JournalOpen Access

Effects of combined changes in serum calcium and potassium on QT interva. A study by holter electrocardiographic monitoring during hemodialysis.

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Why the study?

Do changes in serum calcium and potassium during hemodialysis affect the QT interval in patients on chronic hemodialysis?

Population

20 patients on chronic hemodialysis

Comparison

5-hour hemodialysis vs Predialysis baseline

Design

Cohort

Follow-up

24 hours

Authors

RARafique AhmedPakistan Telecommunication Company (Pakistan)FKFumihiro KiyaNagasaki University KKK. KitanoNagasaki University

Discussion

Member takes

Implication

Electrolyte shifts may modify QT subintervals during hemodialysis; hypothesis-generating for arrhythmic risk in chronic dialysis patients.

Structured PICO

Do changes in serum calcium and potassium during hemodialysis affect the QT interval in patients on chronic hemodialysis?

Population

20 patients on chronic hemodialysis

Intervention

5-hour hemodialysis

Comparator

Predialysis baseline

Outcome

Changes in Q-oTc and Q-eTc intervals on 24-hour Holter monitoringsurrogate

During hemodialysis, increased serum calcium shortens the Q-oTc interval while decreased serum potassium prolongs the Q-eTc interval.

Cite This Study

Ahmed et al. (1987) studied this question.

synapsesocial.com/papers/6a1c0ddf1567d2fc4d5f8352 https://doi.org/10.1536/ihj.28.813

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Implication

Electrolyte shifts may modify QT subintervals during hemodialysis; hypothesis-generating for arrhythmic risk in chronic dialysis patients.