Why the study?
Does catheter-based renal denervation reduce ambulatory heart rate in hypertensive patients not receiving anti-hypertensive medications?
Does catheter-based renal denervation reduce ambulatory heart rate in hypertensive patients not receiving anti-hypertensive medications?
Catheter-based renal denervation significantly reduces morning heart rate at 3 months compared to sham in unmedicated hypertensive patients, and higher baseline heart rate may predict greater blood pressure reduction.
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Supports broader autonomic effects of RDN beyond BP; extends sham-controlled trials to ambulatory HR in unmedicated hypertension.
Average and minimum morning HR were significantly reduced at 3 months for RDN compared with sham patients. A baseline 24-h HR above the median predicted greater BP reductions and may allow physicians to select patients likely to respond to the procedure.
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Böhm et al. (2018) studied this question.
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