Does Tongxinluo attenuate atherosclerosis by inhibiting endothelial cell pyroptosis?
Tongxinluo attenuates atherosclerosis by inhibiting ROS/NLRP3/caspase-1-mediated endothelial cell pyroptosis.
Our results indicated that TXL inhibited EC pyroptosis in AS. Reducing the accumulation of ROS may be the essential mechanism of AS inhibition by TXL.
Jiang et al. (Thu,) studied this question.