March 21, 2017Circulation ResearchOpen Access

20-HETE Signals Through G-Protein–Coupled Receptor GPR75 (G q ) to Affect Vascular Function and Trigger Hypertension

View Full Paper

Ask AI

Bookmark

Population

Molecular target (GPR75 receptor) for 20-HETE

Design

Preclinical

Authors

Discussion

Positions GPR75 as a novel hypertension target; leaves open clinical translation from animal models.

Population

Molecular target (GPR75 receptor) for 20-HETE

Intervention

20-HETE

Outcome

Identification of GPCR target for 20-HETEsurrogate

The identification of GPR75 as the receptor for 20-HETE provides a novel molecular mechanism for its role in hypertension and cardiovascular disease.

García et al. (2017) studied this question.

View Full Paper

Ask AI

Bookmark