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February 23, 2004Nucleic Acids ResearchOpen Access

ARB: a software environment for sequence data

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Authors

WLWolfgang LudwigUniversity of Stuttgart

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Implication

Software evaluation demonstrates integrated database maintenance and phylogenetic analysis across nucleic and amino acid sequences, highlighting broad utility in computational biology.

Key Points

  • To develop and provide a comprehensive software environment for sequence database management, alignment, and phylogenetic tree-based analysis.
  • Engineered an integrated graphical software suite combining database maintenance tools with biological sequence analysis features.
  • Implemented a central database storing aligned primary structures alongside descriptive metadata linked locally or via networks.
  • Built specialized modules for sequence alignment, secondary structure editing, phylogenetic analysis, and hybridization probe design.
  • Software supports analysis across both nucleic acid and amino acid sequence datasets, extending beyond its initial ribosomal RNA focus.
  • Integrated phylogenetic trees into the main user interface to directly serve as an intuitive mechanism for data navigation and visualization.

Cite This Study

Wolfgang Ludwig (2004) studied this question.

synapsesocial.com/papers/69d8179952654bb436d17db3https://doi.org/10.1093/nar/gkh293
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