Why the study?
What are the prognostic factors for relapse in patients with nonmetastatic Ewing's sarcoma of bone treated with adjuvant chemotherapy?
What are the prognostic factors for relapse in patients with nonmetastatic Ewing's sarcoma of bone treated with adjuvant chemotherapy?
Chemotherapy-induced necrosis is the most important prognostic factor in surgically treated patients with nonmetastatic Ewing's sarcoma.
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Necrosis grading should inform relapse risk counseling in surgically treated Ewing sarcoma; leaves open prospective validation for treatment adaptation.
Bacci et al. (2000) studied this question.
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