Why the study?
Does acute oral L-arginine supplementation increase nitric oxide production in healthy males?
Population
17 healthy males
Comparison
6 g of oral L-arginine supplementation vs Placebo (as corn starch)
Design
RCT, randomized, double-blind
Follow-up
120 minutes
Authors
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Acute L-arginine does not elevate NOx in healthy males; challenges supplementation rationale and redirects research to endothelial dysfunction cohorts.
Does acute oral L-arginine supplementation increase nitric oxide production in healthy males?
Acute oral L-arginine supplementation does not increase plasma NOx concentrations in healthy males with normal baseline ADMA levels.
Álvares et al. (2012) studied this question.
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