Key result
Acute L-arginine supplementation reduced steady-state O2 uptake during moderate-intensity exercise (1.48 vs 1.59 l/min, P<0.05) and extended time to exhaustion during severe-intensity exercise.
Why the study?
Does acute L-arginine supplementation reduce the O2 cost of moderate-intensity exercise and enhance high-intensity exercise tolerance in healthy men?
Population
9 healthy men (aged 19-38 yr)
Comparison
500 ml beverage containing 6 g of L-arginine… vs Placebo beverage
Design
Other, double-blind
Follow-up
1 h after ingestion
Authors
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L-arginine may enhance exercise economy in healthy adults; extends nitrate findings to direct NOS substrate supplementation.
RCT (n=9)
Double-blind
Does acute L-arginine supplementation reduce the O2 cost of moderate-intensity exercise and enhance high-intensity exercise tolerance in healthy men?
Absolute Event Rate: 1.48% vs 1.59%
p-value: p=< 0.05
Acute L-arginine supplementation improves exercise efficiency and tolerance in healthy young men, likely by increasing nitric oxide bioavailability.
Bailey et al. (2010) conducted an RCT in Healthy (n=9). l-arginine vs. Placebo was evaluated on Steady-state O2 uptake (VO2) during moderate-intensity exercise (p=< 0.05). Acute L-arginine supplementation reduced steady-state O2 uptake during moderate-intensity exercise (1.48 vs 1.59 l/min, P<0.05) and extended time to exhaustion during severe-intensity exercise.
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