Why the study?
This study evaluated the effects of short-term oral L-arginine supplementation on vascular parameters, nitric oxide concentration, and muscular performance during upper limb resistance exercise in healthy young men.
Does short-term oral L-arginine supplementation improve muscular endurance and vascular function during resistance exercise in healthy young men?
Population
16 recreationally trained men
Comparison
Oral L-arginine (3.2-9.6 g/day) vs placebo
Design
Randomized, double-blind, crossover study
Follow-up
4 days
Authors
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No ergogenic benefit from short-term L-arginine; challenges prior claims and leaves open larger trials in other populations.
Does short-term oral L-arginine supplementation improve muscular endurance and vascular function during resistance exercise in healthy young men?
Short-term oral L-arginine supplementation does not provide meaningful ergogenic benefits or enhance systemic nitric oxide and vascular function during resistance exercise in healthy young men.
Borges et al. (2025) studied this question.
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