Key result
Acute oral supplementation with 6 g of L-arginine did not significantly improve O2 consumption kinetics or muscle oxygenation variables compared to placebo during treadmill running.
Why the study?
L-arginine is used to improve sports performance and enhance muscular recovery during exercise, but existing literature remains inconclusive.
Does acute oral L-arginine supplementation improve O2 consumption kinetics and muscle oxygenation during treadmill running in young healthy male adults?
Population
11 young healthy male adults
Comparison
6 g of oral L-arginine vs placebo
Design
Double-blind, crossover, placebo-controlled randomized trial
Follow-up
6 min after exercise
Authors
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Acute L-arginine shows no benefit on O2 kinetics or muscle oxygenation during running; leaves open questions on chronic dosing or other populations.
RCT (n=11)
Double-blind
Randomized crossover
Does acute oral L-arginine supplementation improve O2 consumption kinetics and muscle oxygenation during treadmill running in young healthy male adults?
Acute oral L-arginine supplementation (6 g) does not improve oxygen consumption kinetics or muscle oxygenation during treadmill running in young healthy males.
Meirelles et al. (2019) conducted an RCT in Healthy (n=11). L-arginine vs. Placebo was evaluated on O2 consumption kinetics and local muscle blood volume and oxygenation. Acute oral supplementation with 6 g of L-arginine did not significantly improve O2 consumption kinetics or muscle oxygenation variables compared to placebo during treadmill running.
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