The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination

4,095 adults having at least one parent in the Offspring Cohort, along with 103 parents of Third Generation Cohort participants who were not previously enrolled in the Offspring Cohort. 1,912 men and 2,183 women consented and attended the first examination (mean age: 40 ± 9 years; range: 19-72 years).