Why the study?
Does ARB therapy slow the rate of progressive aortic-root dilation in patients with Marfan's syndrome?
Does ARB therapy slow the rate of progressive aortic-root dilation in patients with Marfan's syndrome?
ARB therapy may significantly slow progressive aortic-root dilation in patients with Marfan's syndrome, though randomized trials are needed to confirm these findings.
May support ARB consideration in Marfan syndrome; leaves open confirmation by randomized trials.
In a small cohort study, the use of ARB therapy in patients with Marfan's syndrome significantly slowed the rate of progressive aortic-root dilation. These findings require confirmation in a randomized trial.
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Brooke et al. (2008) studied this question.
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