Does the presence of TTNtv worsen left ventricular ejection fraction in DCM patients who consume alcohol above recommended levels?
Familial evaluation and genetic testing should be considered in patients presenting with alcoholic cardiomyopathy due to the prevalent genetic predisposition of TTNtv.
TTNtv represent a prevalent genetic predisposition for ACM, and are also associated with a worse left ventricular ejection fraction in DCM patients who consume alcohol above recommended levels. Familial evaluation and genetic testing should be considered in patients presenting with ACM.
Ware et al. (Tue,) studied this question.