Despite immediate admission to specialized stroke units, 4.5% of patients with TIA or minor stroke experience early clinical deterioration, highlighting the need to address coexistent acute infection and cardiac decompensation.
May warrant monitoring for infection and cardiac decompensation in TIA patients; leaves open whether targeted intervention reduces deterioration.
Our study revealed a high rate of early clinical deterioration (4.5%) among 8,291 patients with TIA or minor stroke despite immediate admission to specialized stroke units. Predictors for neurologic deterioration apart from diabetes, hypertension, and the estimated ABCD2 score were stroke etiology, reinforcing the relevance of an immediate diagnostic workup, and coexistent acute infection and cardiac decompensation, both conditions necessitating adequate attention in the emergency setting.
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Ferrari et al. (2010) studied this question.
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