January 19, 2023Science
CRISPR technology: A decade of genome editing is only the beginning
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Implication
Review uncovers a decade of CRISPR genome editing advances across humans, animals, and plants, highlighting expanding therapeutic and agricultural applications.
Key Points
- To synthesize the progress, clinical and agricultural achievements, limitations, and future roadmap of CRISPR-mediated genome editing over its first decade of application.
- Narrative review synthesizing a decade of breakthroughs in CRISPR-based genome editing.
- Analysis of genome editing tools integrated with computational advances and imaging technologies.
- Evaluation of biological applications across human cell models, animal systems, and crop species.
- CRISPR-mediated editing enables actionable interventions for predicting and modifying genetic disease susceptibilities in human and animal cells.
- Genome editing transforms agricultural breeding by accelerating the identification and modification of targeted plant traits.
- Future clinical and agricultural translation depends on overcoming persistent delivery, precision, and implementation challenges.
Cite This Study
Wang et al. (2023) studied this question.