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April 10, 2026Heart and MindOpen Access

Stress-induced cardiomyopathy linked to LV thrombus and acute stroke despite therapeutic anticoagulation.

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Population

A 72-year-old female patient with stress-induced cardiomyopathy and acute cerebral infarction

Design

Case report

Follow-up

6 months

Key result

Stress-induced cardiomyopathy triggered by emotional trauma can lead to left ventricular thrombus and acute cerebral infarction despite therapeutic anticoagulation.

Authors

PRPeijun RaoCQChangjiang QinGLGuo Li

Discussion

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Overview

Warrants vigilance and early imaging for LV thrombus in stress cardiomyopathy; extends evidence of embolic risk despite anticoagulation and remains hypothesis-generating.

Key Points

  • To explore the mechanisms linking stress-induced cardiomyopathy with acute cerebral infarction in a clinical case.
  • Case report of a 72-year-old female with symptoms of chest pain and neurological deficits.
  • Sequential electrocardiograms and echocardiograms were conducted during the hospital stay.
  • Coronary computed tomography angiography was performed to assess coronary artery condition and stenosis.
  • Magnetic resonance imaging was used to evaluate cerebral and cardiac status at multiple time points.
  • The patient exhibited significant emotional stress prior to hospitalization, correlating with myocardial injury.
  • Stenosis was found in multiple coronary arteries, but no severe blockage indicative of acute myocardial infarction was present.
  • Echocardiogram revealed improved ejection fraction from 43% at admission to 65% by day 10, indicating recovery from myocardial injury.
  • An embolus was identified in the left middle cerebral artery, leading to urgent thrombectomy.

Structured PICO

P
Population
1 72-year-old female patient with stress-induced cardiomyopathy (SCM) complicated by acute cerebral infarction and left ventricular thrombus, with a history of hypertension and diabetes.
I
Intervention
Therapeutic anticoagulation with rivaroxaban 20 mg daily, cranial artery thrombectomy, and supportive care.

This case highlights that stress-induced cardiomyopathy can be complicated by rapid left ventricular thrombus formation and severe systemic embolism, emphasizing the need for vigilance and appropriate imaging.

Cite This Study

Rao et al. (2026) studied this question. Stress-induced cardiomyopathy triggered by emotional trauma can lead to left ventricular thrombus and acute cerebral infarction despite therapeutic anticoagulation.

synapsesocial.com/papers/69d893626c1944d70ce04588https://doi.org/10.4103/hm.hm-d-25-00083
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Takotsubo cardiomyopathy mimicking postoperative myocardial infarction in a young healthy patient2013 · 4 citations
  2. 2COVID-19-induced takotsubo cardiomyopathy: Venturing beyond the obvious2021 · 6 citations
  3. 3Case series of electrocardiograms in neurocardiology2026
  4. 4Acute and reversible cardiomyopathy provoked by stress in a Chinese woman2008 · 1 citations
  5. 5Clinical Characteristics and Prognostic Factors of Stress-Induced Cardiomyopathy2010 · 30 citations