Case report reveals link between alpha-gal syndrome and transfusion reactions in non-B individuals, suggesting new clinical practices.
This case demonstrates a possible clinical association between AGS and anaphylactic transfusion reaction to group B blood products in non-B recipients. Early laboratory workups for AGS antibodies are recommended in non-B patients with a history of tick exposure and severe allergic reactions to meat consumption or transfusion of group B blood products. Meanwhile, transfusion of group B blood products should be avoided once AGS is suspected clinically in non-B patients.
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Hinojosa et al. (2026) studied this question.
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