A systematic review reports higher neuromyelitis optica spectrum disorder prevalence in Brazil, suggesting regional variations.
This study provides an integrated evaluation of NMOSD prevalence through a global systematic review, a regional population-based analysis in southeastern Brazil, and a meta-analysis, demonstrating that prevalence in this region is higher than the global pooled estimate and consistent with the higher prevalence observed in the Americas, particularly in populations with substantial African ancestral backgrounds.
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Alvarenga et al. (2026) studied this question.
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