Catalytic desymmetrization develops complex chiral architectures in prochiral compounds, suggesting new synthesis pathways.
The catalytic desymmetrization of prochiral molecules provides a powerful and step-economical strategy for constructing complex chiral architectures. Herein, we report a general organocatalytic asymmetric cycloaddition desymmetrization of both biaryl and...
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Hu et al. (2026) studied this question.
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