Explores the generation of free radicals and their impact on stability and reactivity in biological systems.
Free radicals are a chemical species that possess unpaired electrons.These electrons account for their reduced chemical stability and high reactivity.They are produced continuously within the cells.The important free radicals generated in the body are derivatives of oxygen and are termed Reactive Oxygen Species (ROS), eg.super oxide radical, hydroxyl radical, peroxy radical, hydrogen peroxide, singlet oxygen, nitric oxide radical, peroxynitrite, 1 hypochlorous acid, etc . Chemistry of free radical generationThe outermost orbital of an atom contains paired electrons, which account for its chemical stability.But loss of one electron makes it unstable and highly reactive (Fig. 1).
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K Abraham Jose (2010) studied this question.
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