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Review the clinical implications of carbapenem resistance in Gram-negative pathogens and discuss potential future approaches to address this global health challenge.

December 10, 2015Therapeutic Advances in Infectious DiseaseOpen Access

Carbapenem resistance: overview of the problem and future perspectives

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GMGeorgios MeletisAristotle University of Thessaloniki

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Implication

Literature review reveals rapid dissemination of carbapenem resistance in Gram-negative bacteria, highlighting severe therapeutic limitations and urgent public health threats.

Key Points

Review the clinical implications of carbapenem resistance in Gram-negative pathogens and discuss potential future approaches to address this global health challenge.
Examined scientific evidence regarding the mechanisms driving carbapenem resistance in Gram-negative bacteria.
Assessed the epidemiology of transferable carbapenemase-encoding genes and their role in driving hospital outbreaks.
Carbapenem resistance continues to spread globally, primarily propelled by mobile, transferable carbapenemase-encoding genes.
The ongoing emergence and transmission of resistant Gram-negative strains severely restricts remaining therapeutic options for affected patients.

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Georgios Meletis (2015) studied this question.

synapsesocial.com/papers/69d895fade3177251abed8fb https://doi.org/10.1177/2049936115621709

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Implication

Literature review reveals rapid dissemination of carbapenem resistance in Gram-negative bacteria, highlighting severe therapeutic limitations and urgent public health threats.

Carbapenem resistance: overview of the problem and future perspectives

Discussion

Member takes

Implication

Key Points

Cite This Study

Carbapenem resistance: overview of the problem and future perspectives

Discussion

Member takes

Implication

Key Points

Cite This Study

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