February 24, 2004Circulation
Randomized Study to Evaluate Sirolimus-Eluting Stents Implanted at Coronary Bifurcation Lesions
Why the study?
Do sirolimus-eluting stents improve outcomes compared with bare metal stents in coronary bifurcation lesions?
Population
Patients with coronary bifurcation lesions
Comparison
Sirolimus-eluting stents (Cypher stent) vs Historical controls using bare metal stents
Design
RCT, Randomized
Authors
Discussion
Loading...
Member takes
Implication
Sirolimus-eluting stents merit randomized trials in bifurcations; observational data should not yet change practice.
Structured PICO
Do sirolimus-eluting stents improve outcomes compared with bare metal stents in coronary bifurcation lesions?
P
Population
Patients with coronary bifurcation lesions
I
Intervention
Sirolimus-eluting stents (Cypher stent)
C
Comparator
Historical controls using bare metal stents
Sirolimus-eluting stents offer improvement over bare metal stents for coronary bifurcation lesions, but side branch restenosis remains a challenge.
Limitations
- No statement can be made regarding the most appropriate technique to use when treating bifurcations with the Cypher stent
Cite This Study
Colombo et al. (2004) studied this question.