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March 1, 1998Molecular and Cellular BiologyOpen Access

Regulation of the p85/p110 Phosphatidylinositol 3′-Kinase: Stabilization and Inhibition of the p110α Catalytic Subunit by the p85 Regulatory Subunit

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Authors

JYJinghua YuShihezi UniversityYZYitao ZhangAlbert Einstein College of MedicineJMJames McIlroy

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Yu et al. (1998) studied this question.

synapsesocial.com/papers/69d8da67ade63f05b9bedb5chttps://doi.org/10.1128/mcb.18.3.1379
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activation of Phosphatidylinositol-3′ Kinase by Src-Family Kinase SH3 Binding to the p85 Subunit1994 · 437 citations
  2. 2Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.1994 · 396 citations
  3. 3Phosphatidylinositol 3-Kinase Activity Is Required at a Postendocytic Step in Platelet-derived Growth Factor Receptor Trafficking1995 · 168 citations
  4. 4Specific Activation of p85-p110 Phosphatidylinositol 3′-Kinase Stimulates DNA Synthesis by ras- and p70 S6 Kinase-Dependent Pathways1997 · 70 citations
  5. 5Cpk Is a Novel Class of Drosophila PtdIns 3-Kinase Containing a C2 Domain1996 · 67 citations