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Supports genetic screening in ARVC families; leaves open targeted therapy development.
Arrhythmogenic right ventricular cardiomyopathy is a heritable heart-muscle disorder that causes progressive replacement of right ventricular myocardium by fibrofatty tissue. Mutations in genes encoding desmosomal proteins play a key role in the pathogenesis of the disease.
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Corrado et al. (2017) studied this question.
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