Evidence for structural and functional abnormality in the subgenual anterior cingulate cortex in major depressive disorder

This is the authors' abstract. We don't add key points for this paper.

Whole-brain, voxel-based analysis finds evidence of both structural and functional abnormality in the sgACC in major depressive disorder. The fact that the functional changes in this area took the form of failure of deactivation adds to previous findings of default mode network dysfunction in the disorder.