The role of teichoic acid in the adherence of Staphylococcus aureus to nasal epithelial cells was investigated. Epithelial cells treated with teichoic acid demonstrated decreased binding of S. aureus. A 71% reduction of adherence was noted with teichoic acid-treated epithelial cells as compared with controls (P less than 0.001). Reduction in adherence of S. aureus was also noted with lipoteichoic acid (obtained from streptococci)-treated epithelial cells. The data provide evidence that teichoic acid mediates the adherence of S. aureus to nasal mucosal cells.
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Aly et al. (1980) studied this question.
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