Does sex affect baseline platelet reactivity and response to aspirin and clopidogrel monotherapy?
Females have higher baseline platelet reactivity and lower responsiveness to standard antiplatelet monotherapies compared to males, highlighting a potential need for sex-specific antiplatelet strategies.
Females exhibit heightened baseline ADP-dependent platelet reactivity and a diminished response to aspirin and clopidogrel monotherapy compared to males.
Galli et al. (Tue,) studied this question.