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May 22, 2013BMC CancerOpen Access

Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer

Bhupendra Singh Anwesha Chatterjee Amruta Ronghe Nimee K. Bhat Hari K. Bhat

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Abstract

Our studies suggest that antioxidants Vit C and BHA provide protection against oxidative DNA damage and E2-induced mammary carcinogenesis, at least in part, through NRF2-mediated induction of OGG1.

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Singh et al. (2013) studied this question.

synapsesocial.com/papers/69d93ad97fca1f84ab6846d4 https://doi.org/10.1186/1471-2407-13-253

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