Why the study?
Does MPO-Gd enable noninvasive in vivo assessment of myeloperoxidase activity and detect the antiinflammatory effects of atorvastatin in ischemia-reperfusion injury?
Does MPO-Gd enable noninvasive in vivo assessment of myeloperoxidase activity and detect the antiinflammatory effects of atorvastatin in ischemia-reperfusion injury?
MPO-Gd provides a noninvasive imaging approach to evaluate myocardial inflammation and the efficacy of cardioprotective therapies such as atorvastatin.
MPO-Gd enables in vivo assessment of MPO activity in injured myocardium. This approach allows noninvasive evaluation of the inflammatory response to ischemia and has the potential to guide the development of novel cardioprotective therapies.
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Nahrendorf et al. (2008) studied this question.
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