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Reveals that the novel plasmid pEM1 derives from the Asia plasmid in ST502 gonococci, indicating localized plasmid evolution in drug-resistant strains.
Sequencing of a novel β-lactamase-encoding plasmid (pEM1) found in PPNG isolates in Johannesburg shows it to be a deletion derivative of the prototype Asia plasmid, the deletion most likely arising as a result of DNA rearrangements. The majority of Johannesburg plasmid-containing PPNG isolates were, or were very closely related to, ST502.
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Müller et al. (2011) studied this question.
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