Fibrinolysis for Patients with Intermediate-Risk Pulmonary Embolism
Why the study?
Does fibrinolytic therapy prevent hemodynamic decompensation in patients with intermediate-risk pulmonary embolism?
Population
patients with intermediate-risk pulmonary embolism
Authors
Discussion
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Member takes
Implication
Reserve fibrinolysis for high-risk cases; confirms net harm with routine use in intermediate-risk pulmonary embolism.
Structured PICO
Does fibrinolytic therapy prevent hemodynamic decompensation in patients with intermediate-risk pulmonary embolism?
P
Population
patients with intermediate-risk pulmonary embolism
I
Intervention
fibrinolytic therapy
O
Outcome
hemodynamic decompensationhard clinical
Fibrinolytic therapy prevents hemodynamic decompensation in intermediate-risk pulmonary embolism but significantly increases the risk of major hemorrhage and stroke.
Cite This Study
Meyer et al. (2014) studied this question.