Prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe morbidity: a WHO individual participant data meta-analysis

Ioannis Gallos; Caitlin R. Williams; Malcolm J Price; Aurelio Tobı́as; Adam Devall; John Allotey; Fernando Althabe; Jenny A. Cresswell; Jill Durocher; A. Metin Gülmezog̈lu; Christian Haslinger; Rodolfo C. Pacagnella; Loïc Sentilhes; Soha Sobhy; Idnan Yunas; Jonathan J Deeks; Arri Coomarasamy; Olufemi T. Oladapo; Anderson Borovac‐Pinheiro; Guillermo Carroli; Arri Coomarasamy; Jill Durocher; Fadhlun M. Alwy Al‐beity; Sue Fawcus; Mario Festin; Hadiza Galadanci; Shivaprasad S. Goudar; A. Metin Gülmezog̈lu; Christian Haslinger; G Justus Hofmeyr; Pisake Lumbiganon; Kidza Mugerwa; Rodolfo de Carvalho Pacagnella; Zahida Qureshi; Loı̈c Sentilhes; L. Sheikh; John Allotey; Arri Coomarasamy; Adam Devall; Jonathan J Deeks; Malcolm J Price; Soha Sobhy; Aurelio Tobias; Idnan Yunas; Fernando Althabe; Jenny A. Cresswell; Ioannis Gallos; Olufemi T. Oladapo; Caitlin R. Williams

doi:10.1016/s0140-6736(25)01639-3

October 1, 2025The LancetOpen Access

Prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe morbidity: a WHO individual participant data meta-analysis

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Key Points

To assess the prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe maternal morbidity.
Conducted a World Health Organization individual participant data meta-analysis synthesizing patient-level data.
Evaluated clinical markers and measurements of postpartum bleeding as prognostic indicators for adverse maternal outcomes.
Assessed clinical bleeding markers to determine their prognostic capacity in identifying women at risk of maternal death and severe morbidity.
Specific quantitative accuracy metrics, effect sizes, and diagnostic thresholds were not reported in the available abstract text.

Implication

Individual participant data meta-analysis reveals prognostic accuracy of bleeding markers in postpartum women, highlighting clinical indicators that predict severe maternal morbidity.

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Cite This Study

Gallos et al. (2025) studied this question.

synapsesocial.com/papers/69d97bd994760e72e6a3cb5d https://doi.org/10.1016/s0140-6736(25)01639-3

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Prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe morbidity: a WHO individual participant data meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Prognostic accuracy of clinical markers of postpartum bleeding in predicting maternal mortality or severe morbidity: a WHO individual participant data meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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