Can electroanatomical voltage mapping accurately identify fibrosis using distinct voltage cut-offs in patients with non-ischaemic cardiomyopathy and ventricular tachycardia?
In non-ischaemic cardiomyopathy, distinct voltage cut-offs cannot reliably identify fibrosis due to linear relationships with wall thickness, and criteria derived from ischaemic substrates may not be applicable.
Considering the linear relationships between WT, amount of fibrosis and both UV and BV, the search for any distinct voltage cut-off to identify fibrosis in NICM is futile. The amount of fibrosis can be calculated, if WT and voltages are known. Fibrosis pattern and architecture are different from ischaemic cardiomyopathy and findings on ischaemic substrates may not be applicable to NICM.
Glashan et al. (Fri,) studied this question.