Key result
Three-dimensional electroanatomic voltage mapping enhanced ARVC/D diagnostic accuracy by identifying low-voltage areas associated with fibrofatty myocardial replacement (P<0.0001).
Why the study?
Does three-dimensional electroanatomic voltage mapping increase the accuracy of diagnosing Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia in patients fulfilling noninvasive diagnostic criteria?
Observational (n=31)
Does three-dimensional electroanatomic voltage mapping increase the accuracy of diagnosing Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia in patients fulfilling noninvasive diagnostic criteria?
p-value: p=<0.0001
Three-dimensional electroanatomic voltage mapping enhances the diagnostic accuracy of ARVC/D by identifying low-voltage areas corresponding to fibrofatty replacement and differentiating true ARVC/D from inflammatory cardiomyopathy mimics.
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May aid ARVC/D differentiation in selected patients; hypothesis-generating and requires prospective validation before practice change.
Corrado et al. (2005) conducted an observational in Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) (n=31). Three-dimensional electroanatomic voltage mapping vs. Normal electroanatomic voltage mapping was evaluated on Association of low-voltage areas with myocyte loss and fibrofatty replacement at endomyocardial biopsy (p=<0.0001). Three-dimensional electroanatomic voltage mapping enhanced ARVC/D diagnostic accuracy by identifying low-voltage areas associated with fibrofatty myocardial replacement (P<0.0001).
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