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February 1, 2013Circulation Arrhythmia and ElectrophysiologyOpen Access

Prognostic Value of Endocardial Voltage Mapping in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia

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Why the study?

Does the extent of bipolar right ventricular endocardial low-voltage area predict arrhythmic outcomes in patients with ARVC/D?

Population

69 consecutive patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia, median age 35 years…

Design

Cohort

Follow-up

median 41 (28-56) months

Authors

Federico Migliore
Federico MiglioreElectrophysiology
AZAlessandro ZorziElectrophysiologyMSMaria SilvanoIstituto Oncologico Veneto

Discussion

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Overview

Low-voltage burden may refine arrhythmic risk stratification in ARVC/D; leaves open prospective validation beyond current models.

Structured PICO

Does the extent of bipolar right ventricular endocardial low-voltage area predict arrhythmic outcomes in patients with ARVC/D?

P
Population
69 consecutive patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), median age 35 years [28-45], 47 males.
I
Intervention
Endocardial voltage mapping (EVM) assessing the extent of bipolar (<1.5 mV) and unipolar (<6.0 mV) low-voltage electrograms
O
Outcome
Arrhythmic events (sudden death, appropriate implantable cardioverter defibrillator interventions, or sustained ventricular tachycardia) during a median follow-up of 41 monthshard clinical

The extent of bipolar right ventricular endocardial low-voltage area on electroanatomic mapping is a strong, independent predictor of arrhythmic events in patients with ARVC/D.

Cite This Study

Migliore et al. (2013) studied this question.

synapsesocial.com/papers/6a70eb64660549caf2c58ffchttps://doi.org/10.1161/circep.111.974881
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Three-Dimensional Electroanatomic Voltage Mapping Increases Accuracy of Diagnosing Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia2005 · 264 citations
  2. 2Implantable Cardioverter/Defibrillator Therapy in Arrhythmogenic Right Ventricular Cardiomyopathy2004 · 293 citations
  3. 3Endocardial Unipolar Voltage Mapping to Detect Epicardial Ventricular Tachycardia Substrate in Patients With Nonischemic Left Ventricular Cardiomyopathy2010 · 411 citations
  4. 4Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia2006 · 250 citations
  5. 5Arrhythmogenic Right Ventricular Cardiomyopathy2012 · 126 citations