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January 2, 2008AIDS

Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance

Edward M. Gardner Shweta Sharma Grace Peng Katherine Huppler Hullsiek William J. Burman Rodger D. MacArthur Margaret A. Chesney Edward E. Telzak Gerald Friedland Sharon Mannheimer

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Abstract

Differential adherence was commonly reported and was associated with an increased risk of initial virological failure and initial virological failure with antiretroviral resistance.

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Cite This Study

Gardner et al. (2008) studied this question.

synapsesocial.com/papers/69d98eb21ad561c67368495a https://doi.org/10.1097/qad.0b013e3282f366ff

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Non-adherence to highly active antiretroviral therapy predicts progression to AIDSCohort Study · 2001 · 960 citations
2Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV InfectionCohort Study · 2000 · 3,289 citations
3The Consistency of Adherence to Antiretroviral Therapy Predicts Biologic Outcomes for Human Immunodeficiency Virus–Infected Persons in Clinical TrialsHuman Clinical Trial · 2002 · 512 citations
4Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent populationCohort Study · 2000 · 1,032 citations
5In Vivo Resistance to a Human Immunodeficiency Virus Type 1 Proteinase Inhibitor: Mutations, Kinetics, and FrequenciesOriginal Research · 1996 · 171 citations

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