What question did this study set out to answer?

To examine whether persistent maternal depressive symptoms across pregnancy and the postpartum period are associated with ADHD symptoms in offspring at ages 3 to 6 years.

December 21, 2017PLoS ONEOpen Access

Maternal depressive symptoms during and after pregnancy are associated with attention-deficit/hyperactivity disorder symptoms in their 3- to 6-year-old children

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Authors

EWElina WolfordUniversity of Helsinki MLMarius Lahti‐PulkkinenRELX Group (Netherlands)STSoile TuovinenUniversity of Helsinki

Discussion

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Implication

Cohort study observes higher ADHD symptoms in young children exposed to maternal depressive symptoms, highlighting the need for pregnancy-tailored mental health interventions.

Key Points

To examine whether persistent maternal depressive symptoms across pregnancy and the postpartum period are associated with ADHD symptoms in offspring at ages 3 to 6 years.
Analyzed 1,779 mother-child dyads from the Prediction and Prevention of Pre-eclampsia and Intrauterine Growth Restriction (PREDO) study.
Assessed maternal depressive symptoms biweekly during pregnancy from 12–14 to 38–40 gestational weeks using the Center of Epidemiological Studies Depression Scale.
Evaluated maternal postnatal depression via the Beck Depression Inventory-II and child ADHD symptoms via the Conners' Hyperactivity Index at child ages 3 to 6 years (mean 3.8 years, SD 0.5).
Children of mothers with consistently high prenatal depressive symptoms exhibited higher average ADHD symptom scores (mean difference = 0.46 SD units, 95% CI 0.36 to 0.56, p < 0.001) compared to the low-symptom group.
Consistently high prenatal depressive symptoms were associated with increased prevalence (32.1% vs. 14.7%) and greater odds of clinically significant ADHD symptoms (OR = 2.80, 95% CI 2.20 to 3.57, p < 0.001).
Postnatal maternal depressive symptoms contributed additively to and partially mediated prenatal effects without fully explaining the association.

Cite This Study

Wolford et al. (2017) studied this question.

synapsesocial.com/papers/69d9aa22387cf7069868506e https://doi.org/10.1371/journal.pone.0190248

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Implication

Cohort study observes higher ADHD symptoms in young children exposed to maternal depressive symptoms, highlighting the need for pregnancy-tailored mental health interventions.

Maternal depressive symptoms during and after pregnancy are associated with attention-deficit/hyperactivity disorder symptoms in their 3- to 6-year-old children

Discussion

Member takes

Implication

Key Points

Cite This Study

Maternal depressive symptoms during and after pregnancy are associated with attention-deficit/hyperactivity disorder symptoms in their 3- to 6-year-old children

Discussion

Member takes

Implication

Key Points

Cite This Study

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