What question did this study set out to answer?

This research aims to develop a non-parametric test that integrates mortality and longitudinal measures in clinical trials for better treatment assessment.

June 15, 1999Statistics in Medicine

Combining mortality and longitudinal measures in clinical trials

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Authors

DFDianne M. FinkelsteinCorvia Medical (United States)DSDavid SchoenfeldHarvard University

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Implication

Randomized trial combines mortality and longitudinal measures to assess treatment benefits, indicating effective evaluation methods.

Key Points

This research aims to develop a non-parametric test that integrates mortality and longitudinal measures in clinical trials for better treatment assessment.
Proposed a non-parametric test combining time to event and longitudinal measures.
Applied the test to AIDS prophylaxis and pediatric clinical trials.
A significant treatment difference on either measure led to rejection of the null hypothesis.
The proposed method showed effectiveness in evaluating therapeutic benefits in clinical settings.

Cite This Study

Finkelstein et al. (1999) studied this question.

synapsesocial.com/papers/69d9b77f5e5bcb4e3b837bb0 https://doi.org/10.1002/(sici)1097-0258(19990615)18:11<1341::aid-sim129>3.0.co;2-7

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Combining mortality and longitudinal measures in clinical trials

Discussion

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Implication

Key Points

Cite This Study

Combining mortality and longitudinal measures in clinical trials

Discussion

Member takes

Implication

Key Points

Cite This Study

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