May 15, 1995Circulation211 citations
View Full PaperEffect of Vasa Vasorum Flow on Structure and Function of the Aorta in Experimental Animals
Structured PICO
P
Population
Experimental animals
I
Intervention
Interruption of vasa vasorum flow (vasa vasorum removal)
O
Outcome
Distensibility of the ascending aorta, structural changes of the aortic wall, and elastic properties of the aortasurrogate
Interruption of vasa vasorum flow impairs aortic distensibility and causes structural changes in the aortic wall in experimental animals.
Abstract
The findings of the present study demonstrated that interruption of vasa vasorum flow led to an acute decrease in the distensibility of the ascending aorta. Moreover, structural changes of the aortic wall and further deterioration of the elastic properties of the aorta occurred 15 days after vasa vasorum removal.