Interruption of vasa vasorum flow impairs aortic distensibility and causes structural changes in the aortic wall in experimental animals.
Should not yet change practice; hypothesis-generating for vasa vasorum role in aortic mechanics.
The findings of the present study demonstrated that interruption of vasa vasorum flow led to an acute decrease in the distensibility of the ascending aorta. Moreover, structural changes of the aortic wall and further deterioration of the elastic properties of the aorta occurred 15 days after vasa vasorum removal.
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Stefanadis et al. (1995) studied this question.
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