April 1, 2007

Association of Increased Cortical Soluble Aβ42 Levels With Diffuse Plaques After Severe Brain Injury in Humans

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Abstract

Selective increases in soluble Abeta(1-42) after TBI may predispose individuals with a brain injury to Alzheimer disease pathology. This may be influenced by the APOE genotype, and it may confer increased risk for developing Alzheimer disease later in life.

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Cite This Study

DeKosky et al. (Sun,) studied this question.

synapsesocial.com/papers/69d9db6f84371aa676a3c359 https://doi.org/https://doi.org/10.1001/archneur.64.4.541

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5Identification of normal and pathological aging in prospectively studied nondemented elderly humans1992 · 642 citations

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