Case report highlights the occurrence of Hb J Meerut hemoglobinopathy in Gujarat, suggesting the need for increased awareness and screening.
Hemoglobin comprises numerous variants, with fast-moving hemoglobin categorized as rare occurrences.These variants are primarily caused by the substitution of a negatively charged amino acid residue in the , , or globin chains.Cation exchange high-performance liquid chromatography (CE-HPLC) is an automated and accurate diagnostic tool for hemoglobinopathies.The -globin variant Hb J Meerut is infrequently observed, having been reported in various populations globally, yet it is notably rare in Gujarat, India.We hereby report two cases of Hb J Meerut hemoglobinopathy in Saurashtra-Kutch region of Gujarat, India.Preventive strategies including pre-marital and antenatal screening, coupled with public awareness and genetic counseling, are vital to mitigate the silent burden of hemoglobinopathies.
No takes yet. Share an insight, caveat, or question.
ANANDANI et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: