S-Wave Amplitude in Lead V3 Identifies Other Electrocardiography Criteria of Left Ventricular Hypertrophy

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The provided text is a technical tutorial on using screencast software for video lessons and contains no clinical research data. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Bernardo Augusto Silveira Corrêa; Gabriel Pinheiro Soares Alencar e Silva; Felipe Campelo de Miranda; Marcio Henrique de Jesus Oliveira; Gabriel Scarpioni Barbosa; Victor Hudson de Lacerda Borges; José Nunes de Alencar

doi:10.36660/ijcs.20250050

January 1, 2026International Journal of Cardiovascular SciencesOpen Access

S-Wave Amplitude in Lead V3 Identifies Other Electrocardiography Criteria of Left Ventricular Hypertrophy

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Key result

Article on S-wave amplitude in lead V3 lacks clinical data and provides a screencast tutorial.

Why the study?

Existing ECG criteria for left ventricular hypertrophy have modest sensitivity and require familiarity with multiple indices, creating a need for simpler markers to improve screening efficiency.

Does S-wave amplitude in lead V3 identify other electrocardiography criteria of left ventricular hypertrophy?

Key Points

To determine whether a single electrocardiographic measurement, the S-wave amplitude in lead V3 (SV3), can accurately identify the presence of established electrocardiographic criteria for left ventricular hypertrophy.
Retrospective diagnostic accuracy analysis evaluating 204 eligible 12-lead ECGs (out of 294 screened) from the PhysioNet PTB diagnostic database.
Established reference criteria for left ventricular hypertrophy included Sokolow-Lyon, Cornell voltage, Sokolow aVL, and Peguero-Lo Presti indices.
Diagnostic performance of SV3 amplitude was evaluated using receiver operating characteristic (ROC) curves, with optimal cutoff determined by Youden and Alencar indices.
SV3 showed good discriminative performance with an area under the curve of 0.8170 (95% CI, 0.7557-0.8783).
An optimal cutoff of ≥ 13 mm achieved a sensitivity of 74.7% (95% CI, 64.4%-82.8%) and a specificity of 78.5% (95% CI, 70.4%-84.9%).
At the ≥ 13 mm threshold, the positive likelihood ratio was 3.476 and the negative likelihood ratio was 0.32.

Structured PICO

Does S-wave amplitude in lead V3 identify other electrocardiography criteria of left ventricular hypertrophy?

I

Intervention

S-wave amplitude in lead V3

Implication

Does not establish S-wave amplitude in V3 for identifying other LVH ECG criteria; leaves open its utility pending dedicated validation.

Abstract

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Cite This Study

Corrêa et al. (2026) studied this question.

synapsesocial.com/papers/69d9e5b378050d08c1b75d83 https://doi.org/10.36660/ijcs.20250050

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S-Wave Amplitude in Lead V3 Identifies Other Electrocardiography Criteria of Left Ventricular Hypertrophy

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

S-Wave Amplitude in Lead V3 Identifies Other Electrocardiography Criteria of Left Ventricular Hypertrophy

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

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