Key result
Localized aortic sinus dissection mimics acute STEMI and requires high-resolution CCTA for diagnosis.
Case Report (n=1)
Localized aortic sinus dissection can mimic acute STEMI, highlighting the need for advanced imaging and the potential role of adaptive PCI as a bridge to definitive surgery.
Warrants coronary CTA prior to catheterization in STEMI with aortic root disease; extends known mimics and is hypothesis-generating.
BACKGROUND: Localized aortic sinus dissection is a rare cause of acute coronary syndrome that is often undetected on initial imaging. CASE SUMMARY: A 72-year-old man with aortic root aneurysm presented with acute inferior ST-segment elevation myocardial infarction (STEMI). Initial computed tomography was negative for aortic dissection, however angiography revealed total occlusion of the right coronary artery (RCA) owing to coronary artery dissection. Percutaneous coronary intervention (PCI), challenging given an anomalous RCA ostium, successfully stented the occlusion. Subsequent high-resolution coronary computed tomography angiography identified right aortic sinus intimal tears extending into the RCA ostium; retrospective review of pre-PCI imaging confirmed dissection. The patient underwent Bentall surgery with RCA bypass. DISCUSSION: This case highlights a localized aortic sinus dissection mimicking primary coronary disease, emphasizing the importance of advanced imaging and the role of adaptive PCI as a bridge to definitive surgery. TAKE-HOME MESSAGES: Localized aortic sinus dissection can mimic acute STEMI and should be considered in patients with known aortic root disease, even when initial imaging appears unremarkable. High-resolution coronary computed tomography angiography is diagnostic; PCI for anomalous ostia may require advanced techniques. A heart team approach is vital for staged management.
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Liu et al. (2026) conducted a case report in Acute inferior ST-segment elevation myocardial infarction (STEMI) secondary to aortic sinus dissection (n=1). Percutaneous coronary intervention and Bentall surgery was evaluated. A 72-year-old man with acute inferior STEMI was found to have a localized aortic sinus dissection extending into the RCA ostium, successfully managed with PCI as a bridge to Bentall surgery.
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