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A dual strategy approach achieves meta-selective arylation in nitrile-bearing compounds, implying new synthetic pathways.
The meta-selective arylation of simple aliphatic nitirile-bearing arylmethanesulfonic acid derivatives under microwave-accelerated conditions has been developed. Also presents the meta-arylation of 3-phenylpropanoic acid esters tethered to a nitrile template under...
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Kaustubh et al. (2025) studied this question.
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