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January 1, 2026Organic Chemistry FrontiersOpen Access

Photoinduced Sulfanyloximation of Styrenes Using N -Nitrosamines and Thiols

Ken Yamazaki Toshiki Tamura Shuta Akimoto Tomoya Miura

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Key Points

The research aims to develop a new method for selectively adding sulfur and nitrogen atoms to styrenes using nitrosamines and thiols.
Utilized photoinduced reactions to facilitate sulfanyloximation of alkenes
Examined the efficiency of nitrosamines and thiols in the reaction
Analyzed the regioselectivity of the process
Achieved successful sulfanyloximation of various styrenes
Demonstrated high regioselectivity in product formation
Highlighted the potential applications in medicinal chemistry

Implication

Demonstrates the regioselective installation of sulfur and nitrogen atoms in styrenes, suggesting a new method in medicinal chemistry.

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Cite This Study

Yamazaki et al. (2026) studied this question.

synapsesocial.com/papers/69d9e67a78050d08c1b76ed5 https://doi.org/10.1039/d6qo00315j

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