Key result
Low-dose aspirin fails to prolong disability-free survival in healthy elderly but increases major hemorrhage ~38%.
Why the study?
Does Aspirin improve disability-free survival in healthy elderly persons?
Does Aspirin improve disability-free survival in healthy elderly persons?
Aspirin does not provide a net benefit for disability-free survival in healthy elderly individuals and increases the risk of major hemorrhage.
No takes yet. Share an insight, caveat, or question.
Avoid routine aspirin for primary prevention in healthy elderly; challenges observational evidence suggesting benefit.
McNeil et al. (2018) studied this question. Daily low-dose aspirin did not prolong disability-free survival in healthy elderly persons (HR 1.01) but increased the rate of major hemorrhage compared to placebo (3.8% vs. 2.8%; HR 1.38).
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